Focal Irreversible Electroporation

NanoKnife© IRE Results

We have now treated 800 patients since February 2013.

All patients have been meticulously followed up (100% follow up) with high-quality MRIs and biopsies, in addition to being offered validated quality of life questionnaires.

Our current outcomes for focal irreversible electroporation in the primary setting (not after radiotherapy) is:

  • 97% clearance of the primary tumour.
  • 0% ongoing incontinence.
  • Less than 10% erectile dysfunction.
  • 20% chance of retrograde ejaculation
  • No major (Clavien 3 or 4) complications.
  • Less than 20% recurrence in other parts of the prostate (up to 12 year Follow up), one third of which had successful redo treatments.
  • Over 100 patients had focal IRE after prior radiation treatment with no major complications, < 1% major complication, < 10% incontinence and < 40% erectile dysfunction with 80% clearance of the primary tumour and 60% overall tumour control

Our Nanoknife publications can be found here.